Granisetron vs. Granisetron and Dexamethasone on The Reduction of Postoperative Nausea and Vomiting (PONV) After Caesarean Section With Intrathecal Morphine: A Randomised Controlled Trial

Background Intrathecal morphine (ITM) has proven to be excellent in reducing postoperative pain. However, its use is associated with the occurrence of nausea and vomiting (PONV). In this study, we wish compare efficacy between combination therapy granisetron dexamethasone versus alone on (PONV) parturients undergoing elective Caesarean delivery.Method This a prospective double-blinded, randomised controlled trial (RCT) involving 126 American Society Anesthesiologist (ASA) physical status I II deliveries. Subjects were randomly allocated into 2 groups (n = 63), either receive 1 mg intravenous (IV) plus 4 IV (Group A) or B). They assessed at 1, 4, 8, 12 24-hour postoperatively. Episodes nausea, retching, requirement rescue antiemetics these time intervals recorded.Results There are no statistically significant differences retching both 24 h The usage similar subjects.Conclusion comparable prevention PONV receiving intrathecal for section.